New dry age related macular degeneration drug treatment approved in US

Forgive us being just a little excited recently when we read in the ophthalmic press about a new drug treatment receiving approval in the USA that could eventually help those living with dry age-related macular degeneration. It was approved by the FDA on 21st February 2023 after being found to help slow the progression of dry AMD in clinical trials.

The Royal National Institute of Blind People (RNIB) estimates that more than four million people are currently living with signs of age-related macular degeneration (AMD) in the UK.

Dry AMD is one variation of this condition, where the macular, a group of retinal cells at the back of the eye, starts to degenerate. Currently, those living with dry AMD have no treatment options available to them.

However, the approval of a new drug, Syfovre, for use in the USA by the Food and Drug Administration (FDA) provides hope that a treatment for UK-based patients is getting closer.

During these trials, it was administered as an injection into the eye at intervals of between 25 and 60 days.

How can Syfovre benefit people with dry AMD?

During the clinical trials, Syfore was shown to help slow down the progression of dry AMD, even in advanced cases. However, although the deterioration of retinal cells was slowed, patients in the trial didn’t see an improvement in their symptoms. Some also had a slightly higher risk of developing wet AMD compared to the placebo group.

However, more new drug applications have been submitted for review to the FDA, meaning greater options for dry AMD treatments may be available in the near future.

Commenting, Lesley Cree said, “As yet, Syfovre has only been approved for use in the US. However, depending on the results of further trials and patient usage, it may yet be considered for approval as a dry AMD treatment in the UK. We will certainly be keeping a close eye on developments in the hope that we can help our patients to access treatment.”

As the ageing population increases, scientists expect the number of people with age-related eye problems to rise dramatically. You can’t prevent all age-related changes to your eyes, but you can take steps to protect your vision and reduce your risk of serious eye disease in the future. The single most important thing is to attend regular eye examinations so any problems can be detected early.

Please get in touch if you’d like to discuss your eye health or book an appointment.